Although Windows provides an interface to manage hard drives, it comes with very less features. Drive-Thru is a freeware tool which allows you to perform management and actions on your hard drives. You can easily hide drives, lock or disallow autorun on any specific drive. Apart from this, the tool also allows you to substitute and drive with a folder and this can be easily done from the drive substitution interface.
You can also disable any drive easily using the interface. It also provides you with simple hacks to maintain your hard drives.